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- Top Avana is a combination medication used to treat erectile dysfunction and premature ejaculation. It contains 30 mg of dapoxetine and 50 mg of avanafil, with some versions like Top Avana 80 mg offering stronger effects. The drug works by increasing blood flow and delaying ejaculation, improving overall performance. It should be taken about 30 minutes before sexual activity. Only one dose is recommended in 24 hours, and it should be used under medical supervision to ensure safety and effectiveness.