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- Duricef (cefadroxil) is a cephalosporin antibiotic used to treat bacterial infections such as urinary tract infections (UTIs), skin infections, and strep throat. It is available in tablet form, typically in 125 mg, 250 mg, and 500 mg strengths. Duricef works by stopping the growth of bacteria. Generic versions are available and may cost less than brand-name options like Keflex. Always take Duricef exactly as prescribed. Common side effects include nausea and diarrhea.